Post-streptococcal glomerulonephritis (gluh-mare-you-low-neh-FRY-tis) is a kidney problem that sometimes happens after strep bacteria cause a throat or skin infection. Most kids with PSGN get completely better and do not have any long-term kidney problems.
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What happens in PSGN? Inside the kidneys are balls of tiny blood vessels called glomeruli. They clean the blood and remove waste and extra water, which leave the body in urine (pee). About 1‒3 weeks after some strep infections of the throat or skin, the glomeruli may get swollen and irritated. They stop working well, and blood cells and protein can leak into the pee. The kidneys also might not be able to get rid of some of the pee. When this happens, water can leak out of the blood vessels into the body's tissues. This causes swelling in the face, belly, hands, and feet.
How is PSGN treated? PSGN usually gets better on its own. Some kids might need treatment to avoid problems from the buildup of waste and water. Treatment may include changes to the diet, medicine and, in very rare cases, dialysis (a treatment to filter blood when the kidneys can't).